A yellow weather warning for snow has been issued.
Forecasters say outbreaks of rain on Saturday and overnight into Sunday will likely be preceded by a spell of snow.
Herefordshire, Monmouthshire, Worcestershire, Gloucestershire and Shropshire are at risk of disruption.
The warning will be in force from midday on Saturday until 9am on Monday.
Revealed: The main roads in Herefordshire prioritised for repairs
Villagers fustrated over lack of road repairs
New Food and Drink group launched at online event