Officers seized a weighing scales, a crack pipe and mobile phones during early-morning raids in Monmouth.
Gwent Police carried out warrants at two residential addresses in Whitecross Street, Monmouth, under the Misuse of Drugs Act.
Officers searched both addresses and recovered items associated with the production of drugs.
Neighbourhood Inspector for Monmouth Emma Sowrey said: "We will continue to work tirelessly to crack down on the production, sale and supply of illegal drugs in Monmouth.
"The public play a vital role in providing us with important information and we encourage anyone with concerns to get in touch immediately.
“If something doesn’t feel right, it might not be. Don’t wait, report it.
"If you have any concerns about drugs in your area, let us know by calling 101 or messaging us on social media.
"Alternatively, you can report it to Crimestoppers, anonymously, on 0800 555 111."
Hereford bypass construction ‘on track’
Fury at failure to prepare for defence investment
Appeal following collision between car and pedestrian in Herefordshire
Revealed: The main roads in Herefordshire prioritised for repairs
Appeal to find missing Monmouthshire man
Man arrested in connection with stabbing incident
New Food and Drink group launched at online event